Evaluation of pharmacotherapeutic follow-up pharmaceutical services offered to people living with HIV: a literature review
Evaluation of pharmacotherapeutic follow-up pharmaceutical services offered to people living with HIV: a literature review
DOI:
https://doi.org/10.47456/rbps.v24i4.39514Keywords:
HIV, Antiretroviral Therapy of Highly Active, Pharmaceutical Services, Medication Therapy ManagementAbstract
Introduction:
Antiretroviral therapy (ART) has an impact on improving the life expectancy of people living with HIV (PLHIV), although some factors can make it difficult to continue treatment, such as the complexity of pharmacotherapy, drug interactions, adverse effects, therapeutic failures, and non-adherence. Objective: To gather studies that address pharmaceutical follow-up pharmacotherapeutic services offered to PLHIV to describe the clinical results achieved by offering this service to these patients. Methods: This is an integrative literature review. Literature searches were performed in PubMed and LILACS electronic databases, using the Medical Subject Headings (MeSH) descriptors: “HIV”, “pharmaceutical services”, “medication therapy management”, and “pharmaceutical care”. A total of 354 articles were retrieved, of which nine articles were included because they approached the pharmaceutical clinical service of pharmacotherapeutic follow-up. Results: It was possible to observe that the pharmacists who offered the service promoted better adherence to ART, the identification and resolution of drug-related problems, and carried out health education interventions. Conclusion: There are several pharmaceutical services with the potential to bring clinical benefits to this population, with an emphasis on pharmacotherapeutic follow-up services. However, further studies are still needed to robustly assess the clinical, humanistic and economic impact of these services.
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References
World Health Organization. HIV/AIDS: fact sheets. [Internet]. Disponível em: https://www.who.int/news-room/fact-sheets/detail/hiv-aids. Acesso em: 14 de abril de 2020.
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Protocolo clínico e diretrizes terapêuticas para manejo da infecção pelo HIV em adultos. Brasília: Ministério da Saúde, 2018.
Granich R, Gupta S, Williams B. 90-90-90, Epidemic control and ending AIDS: global situation and recommendations. Int J Virol AIDS. 2018;5:43.
Loureiro CV, Reis HC, Magalhães KN, Carmo CP, Leite FM, Passos AB, et al. Quality of life of HIV+ patients undergoing pharmacotherapeutic follow-up. Braz J Pharmac Sci 2012;48(4):711-9.
Castilho JL, Escuder MM, Veloso V, Gomes JO, Jayathilake K, Ribeiro S, et al. Trends and predictors of non-communicable disease multimorbidity among adults living with HIV and receiving antiretroviral therapy in Brazil. J Int AIDS Soc. 2019;22:e25233.
Simões NS, Faleiro FS, Cardoso AM, Trindade IB, Baldoni AO, Cruz GP, et al. Complexidade terapêutica de idosos infectados e não infectados pelo HIV. Rev Bras Farm Hosp Serv Saúde. 2019;8(2):8-13.
Silva VC, Mendes JC, Silveira MR, Violante TA, Oliveira TJ, Braga MG. Use of non-antiretroviral drugs and polypharmacy among people living with HIV starting antiretroviral therapy in Belo Horizonte, Brazil. Res Societ Develop 2022;11(5):1-16.
Conselho Federal de Farmácia. Serviços farmacêuticos diretamente destinados ao paciente, à família e à comunidade: contextualização e arcabouço conceitual. Brasília: Conselho Federal de Farmácia; 2016.
CMM in Primary Care Research Team. The patient care process for delivering comprehensive medication management (CMM): optimizing medication use in patient-centered, team-based care settings. 2018. [Internet]. Disponível em: http://www.accp.com/cmm_care_process. Acesso em: 15 mar 2022.
Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan: a web and mobile app for systematic reviews. System Reviews. 2016;5(210):1-10.
Abah IO, Ojeh VB, Falang KD, Darin KM, Olaitan OO, Agbaji OO. Pharmaceutical care outcomes in an outpatient human immunodeficiency virus treatment center in Jos, Nigeria. J Basic Clin Pharm. 2014;5(3):57- 61.
Cope R, Berkowitz L, Arcebido R, Yeh JY, Trustman N, Cha A. Evaluating the effects of a practice model with pharmacist collaboration on HIV patient co-morbidities. AIDS Patient Care STDS. 2015;29(8):445-53.
Domingues EA, Ferrit-Martín M, Calleja-Hernández MA. Impact of pharmaceutical care on cardiovascular risk among older HIV patients on antiretroviral therapy. Int J Clin Pharm. 2017;39(1):52-60.
Molino CG, Carnevale RC, Rodrigues AT, Visacri MB, Moriel P, Mazzola PG. Impact of pharmacist interventions on drug-related problems and laboratory markers in outpatients with human immunodeficiency virus infection. Ther Clin Risk Manag. 2014;7(10):631-9.
Molino CC, Carnevale RC, Rodrigues AT, Moriel P, Mazzola PG. HIV pharmaceutical care in primary healthcare: improvement in CD4 count and reduction in drug-related problems. Saudi Pharm J. 2017;25(5):724-33.
Resende NH, Miranda SS, Ceccato MB, Haddad JA, Reis AM, Silva DI, Carvalho WS. Drug therapy problems for patients with tuberculosis and HIV/AIDS at a reference hospital. Einstein. 2019;17(4):1-9.
Silveira MP, Guttier MC, Page K, Moreira LB. Randomized controlled trial to evaluate the impact of pharmaceutical care on therapeutic success in HIV-infectedpatients in Southern Brazil. AIDS Behav. 2014;18(Suppl 1):75-84.
Ventura Cerdá JM, Almiñana MA. Programa de atención farmacéutica a pacientes VIH con tratamiento antirretroviral: metodología y documentación. Farm Hospit. 2004;28(Supl 1):72-9.
Cipolle RJ, Strand LM, Morley PC. Pharmaceutical care practice: the patient-centered approach to medication management. 3rd ed. Minnesota: McGraw-Hill Education; 2012.
Valentin AS, Rezende CP, Nascimento YA, Gualberto FM, Mendonça SM, Nascimento MG, Oliveira DR. Aspects involved in the sustainability of the comprehensive medication management services. Res Soc Develop. 2021;10(8):1-16.
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