Palliative approach to symptom control and planning for patients with chronic liver disease, inflammatory bowel disease and in need of endoscopic procedures

Authors

  • Fernando Costa Guzzo Federal University of Espírito Santo image/svg+xml
  • Leonardo Fávaro Pereira Hospital Universitário Cassiano Antonio Moraes
  • Luciana Lofego Gonçalves Federal University of Espírito Santo image/svg+xml
  • Maria da Penha Zago-Gomes Federal University of Espírito Santo image/svg+xml

DOI:

https://doi.org/10.47456/rbps.v26i1.51125

Keywords:

Palliative Care, Gastroenterology, Digestive Endoscopy, Liver Cirrhosis, Hepatocellular Carcinoma

Abstract

Introduction: Palliative care requires an interdisciplinary approach to prevent and alleviate diseases that cause suffering, meeting physical, psychosocial, and spiritual demands, as well as health care resources, to improve the quality of life of patients, families, and caregivers. The gastroenterology specialty treats complex chronic diseases and has an interface with other specialties, including many endoscopic procedures frequently requested in neoplastic, neurological, and other patients. Objectives: To develop an article describing the main situations in the daily practice of a gastroenterologist and the necessary palliative care skills. Methodology: Search for works with the terms “Palliative Care”, “Gastroenterology”, “Digestive Endoscopy”, “Liver Cirrhosis”, and “Hepatocellular Carcinoma”. Results: In Gastroenterology and Hepatology, inflammatory bowel diseases and liver cirrhosis are diagnoses that often require palliative care and should be initiated at diagnosis, including prevention and guidance of complications, symptom management and quality of life. For hepatocellular carcinoma, there are protocols that include a palliative approach, but restricted to disease management. The procedures in digestive endoscopy have a great interface with other specialties, alleviating symptoms, obtaining alternative dietary routes and always individualizing decision-making. Conclusion: Integrating different health professionals in care, with relief of the individual's suffering and improvement of quality of life, in addition to better management of hospital resources. Thinking about palliative care early benefits the patient, the family, public and private institutions that provide health care and society.

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References

Birkner B. Die klinische Gastroenterologie: Luxus oder Standardversorgung? Z Gastroenterol. 2005;43:1285–92. https://doi.org/10.1055/s-2005-858877

Dunn GP. Palliative care: a promising philosophical framework for gastroenterology. Gastroenterol Clin North Am. 2006;35:1–21. https://doi.org/10.1016/j.gtc.2005.12.012

Freitas EV. Tratado de geriatria e gerontologia. 4ª ed. Rio de Janeiro: Guanabara Koogan; 2011.

Freitas RD, Oliveira LCD, Mendes GLQ, Lima FLT, Chaves GV. Barreiras para o encaminhamento para o cuidado paliativo exclusivo: a percepção do oncologista. Saúde Debate. 2022;46:331–45. https://doi.org/10.1590/0103-1104202213306

Radbruch L, De Lima L, Knaul F, Wenk R, Ali Z, Bhatnaghar S, et al. Redefining palliative care: a new consensus-based definition. J Pain Symptom Manage. 2020;60:754–64. https://doi.org/10.1016/j.jpainsymman.2020.04.027

Rogal SS, Hansen L, Patel A, Ufere NN, Verma M, Woodrell CD, et al. AASLD practice guidance: palliative care and symptom-based management in decompensated cirrhosis. Hepatology. 2022;76:819–53. https://doi.org/10.1002/hep.32378

Carvalho RC, Parsons HAF. Manual de cuidados paliativos ANCP / Handbook of palliative care ANCP. 2ª ed. Porto Alegre: Sulina; 2012.

Knaul FM, Farmer PE, Krakauer EL, De Lima L, Bhadelia A, Jiang Kwete X, et al. Alleviating the access abyss in palliative care and pain relief—an imperative of universal health coverage: the Lancet Commission report. Lancet. 2018;391(10128):1391–454. https://doi.org/10.1016/S0140-6736(17)32513-8

Holtmann M, Domagk D, Weber M, Moehler M, Pott G, Ramadori G, et al. Gastroenterologische Palliativmedizin. Z Gastroenterol. 2008;46:712–24. https://doi.org/10.1055/s-2008-1027378

Laugsand EA, Kaasa S, De Conno F, Hanks G, Klepstad P. Intensity and treatment of symptoms in 3030 palliative care patients: a cross-sectional survey of the EAPC Research Network. J Opioid Manag. 2009;5:11–21. https://doi.org/10.5055/jom.2009.0002

Arnstadt B, Allescher HD. Palliative endoscopy. Chirurg. 2022;93:310–22. https://doi.org/10.1007/s00104-021-01426-5

Teunissen SC, Wesker W, Kruitwagen C, De Haes HCJM, Voest EE, De Graeff A. Symptom prevalence in patients with incurable cancer: a systematic review. J Pain Symptom Manage. 2007;34:94–104. https://doi.org/10.1016/j.jpainsymman.2006.10.015

Schütte K, Weigt J, Meyer F, Malfertheiner P. Palliativtherapie im Grenzgebiet zwischen Gastroenterologie und (Viszeral-) Chirurgie. Zentralbl Chir. 2010;135:528–34. https://doi.org/10.1055/s-0030-1262702

Soliman YY, Kundranda M, Kachaamy T. Endoscopic palliative therapies for esophageal cancer. Gastrointest Endosc Clin N Am. 2024;34:91–109. https://doi.org/10.1016/j.giec.2023.07.003

Krouse RS. Malignant bowel obstruction. J Surg Oncol. 2019;120:74–7. https://doi.org/10.1002/jso.25451

Haluszka O. Palliative gastroenterology. Semin Oncol. 2005;32:174–8. https://doi.org/10.1053/j.seminoncol.2004.11.010

Gerson LB, Triadafilopoulos G. Palliative care in inflammatory bowel disease: an evidence-based approach. Inflamm Bowel Dis. 2000;6:228–43. https://doi.org/10.1097/00054725-200008000-00009

Rivet EB, Bohl JL, Al Yassin S, Bickston SJ. Palliative care in inflammatory bowel disease: a new partnership. Crohn’s Colitis 360. 2021;3:otab062. https://doi.org/10.1093/crocol/otab062

Scott LD. Quality medical care in gastroenterology: lessons from palliative medicine. Am J Gastroenterol. 2009;104:1352–5. https://doi.org/10.1038/ajg.2009.142

Drossman DA. Presidential address: gastrointestinal illness and the biopsychosocial model. Psychosom Med. 1998 May-Jun;60(3):258–67. https://doi.org/10.1097/00006842-199805000-00007

Feng L, Cai X, Zou Q, Peng Y, Xu L, Wang L, et al. Exploring the management and treatment of IBD from the perspective of psychological comorbidities. Ther Adv Gastroenterol. 2024 Oct 16;17:17562848241290685. https://doi.org/10.1177/17562848241290685

Langberg KM, Kapo JM, Taddei TH. Palliative care in decompensated cirrhosis: a review. Liver Int. 2018;38:768–75. https://doi.org/10.1111/liv.13620

Tandon P, Walling A, Patton H, Taddei T. AGA clinical practice update on palliative care management in cirrhosis: expert review. Clin Gastroenterol Hepatol. 2021;19:646–56.e3. https://doi.org/10.1016/j.cgh.2020.11.027

Shinall MC, Karlekar M, Martin S, Gatto CL, Misra S, Chung CY, et al. COMPASS: a pilot trial of an early palliative care intervention for patients with end-stage liver disease. J Pain Symptom Manage. 2019;58:614–22.e3. https://doi.org/10.1016/j.jpainsymman.2019.06.023

Lamba S, Murphy P, McVicker S, Harris Smith J, Mosenthal AC. Changing end-of-life care practice for liver transplant service patients: structured palliative care intervention in the surgical intensive care unit. J Pain Symptom Manage. 2012;44:508–19. https://doi.org/10.1016/j.jpainsymman.2011.10.018

Poonja Z, Brisebois A, Van Zanten SV, Tandon P, Meeberg G, Karvellas CJ. Patients with cirrhosis and denied liver transplants rarely receive adequate palliative care or appropriate management. Clin Gastroenterol Hepatol. 2014;12:692–8. https://doi.org/10.1016/j.cgh.2013.08.027

Kathpalia P, Smith A, Lai JC. Underutilization of palliative care services in the liver transplant population. World J Transplant. 2016;6:594–600. https://doi.org/10.5500/wjt.v6.i3.594

Morrison RS, Dietrich J, Ladwig S, Quill T, Sacco J, Tangeman J, et al. Palliative care consultation teams cut hospital costs for Medicaid beneficiaries. Health Aff (Millwood). 2011;30:454–63. https://doi.org/10.1377/hlthaff.2010.0929

Peng JK, Hepgul N, Higginson IJ, Gao W. Symptom prevalence and quality of life of patients with end-stage liver disease: a systematic review and meta-analysis. Palliat Med. 2019;33:24–36. https://doi.org/10.1177/0269216318807051

Will V, Rodrigues SG, Berzigotti A. Current treatment options of refractory ascites in liver cirrhosis: a systematic review and meta-analysis. Dig Liver Dis. 2022;54:1007–14. https://doi.org/10.1016/j.dld.2021.12.007

Shrestha D, Rathi S, Grover S, Taneja S, Duseja A, Chawla YK, et al. Factors affecting psychological burden on the informal caregiver of patients with cirrhosis: looking beyond the patient. J Clin Exp Hepatol. 2020;10:9–16. https://doi.org/10.1016/j.jceh.2019.06.002

Laube R, Sabih A, Strasser SI, Lim L, Cigolini M, Liu K. Palliative care in hepatocellular carcinoma. J Gastroenterol Hepatol. 2021;36:618–28. https://doi.org/10.1111/jgh.15169

Rush B, Walley KR, Celi LA, Rajoriya N, Brahmania M. Palliative care access for hospitalized patients with end‐stage liver disease across the United States. Hepatology. 2017;66:1585–91. https://doi.org/10.1002/hep.29297

Published

2024-12-31

Issue

Section

Dossier: Medical Residency Commission (COREME-HUCAM)

How to Cite

1.
Palliative approach to symptom control and planning for patients with chronic liver disease, inflammatory bowel disease and in need of endoscopic procedures. RBPS [Internet]. 2024 Dec. 31 [cited 2026 Jul. 16];26(1):e51125. Available from: https://periodicos.ufes.br/rbps/article/view/51125