Palliative approach to symptom control and planning for patients with chronic liver disease, inflammatory bowel disease and in need of endoscopic procedures
DOI:
https://doi.org/10.47456/rbps.v26i1.51125Keywords:
Palliative Care, Gastroenterology, Digestive Endoscopy, Liver Cirrhosis, Hepatocellular CarcinomaAbstract
Introduction: Palliative care requires an interdisciplinary approach to prevent and alleviate diseases that cause suffering, meeting physical, psychosocial, and spiritual demands, as well as health care resources, to improve the quality of life of patients, families, and caregivers. The gastroenterology specialty treats complex chronic diseases and has an interface with other specialties, including many endoscopic procedures frequently requested in neoplastic, neurological, and other patients. Objectives: To develop an article describing the main situations in the daily practice of a gastroenterologist and the necessary palliative care skills. Methodology: Search for works with the terms “Palliative Care”, “Gastroenterology”, “Digestive Endoscopy”, “Liver Cirrhosis”, and “Hepatocellular Carcinoma”. Results: In Gastroenterology and Hepatology, inflammatory bowel diseases and liver cirrhosis are diagnoses that often require palliative care and should be initiated at diagnosis, including prevention and guidance of complications, symptom management and quality of life. For hepatocellular carcinoma, there are protocols that include a palliative approach, but restricted to disease management. The procedures in digestive endoscopy have a great interface with other specialties, alleviating symptoms, obtaining alternative dietary routes and always individualizing decision-making. Conclusion: Integrating different health professionals in care, with relief of the individual's suffering and improvement of quality of life, in addition to better management of hospital resources. Thinking about palliative care early benefits the patient, the family, public and private institutions that provide health care and society.
Downloads
References
Birkner B. Die klinische Gastroenterologie: Luxus oder Standardversorgung? Z Gastroenterol. 2005;43:1285–92. https://doi.org/10.1055/s-2005-858877
Dunn GP. Palliative care: a promising philosophical framework for gastroenterology. Gastroenterol Clin North Am. 2006;35:1–21. https://doi.org/10.1016/j.gtc.2005.12.012
Freitas EV. Tratado de geriatria e gerontologia. 4ª ed. Rio de Janeiro: Guanabara Koogan; 2011.
Freitas RD, Oliveira LCD, Mendes GLQ, Lima FLT, Chaves GV. Barreiras para o encaminhamento para o cuidado paliativo exclusivo: a percepção do oncologista. Saúde Debate. 2022;46:331–45. https://doi.org/10.1590/0103-1104202213306
Radbruch L, De Lima L, Knaul F, Wenk R, Ali Z, Bhatnaghar S, et al. Redefining palliative care: a new consensus-based definition. J Pain Symptom Manage. 2020;60:754–64. https://doi.org/10.1016/j.jpainsymman.2020.04.027
Rogal SS, Hansen L, Patel A, Ufere NN, Verma M, Woodrell CD, et al. AASLD practice guidance: palliative care and symptom-based management in decompensated cirrhosis. Hepatology. 2022;76:819–53. https://doi.org/10.1002/hep.32378
Carvalho RC, Parsons HAF. Manual de cuidados paliativos ANCP / Handbook of palliative care ANCP. 2ª ed. Porto Alegre: Sulina; 2012.
Knaul FM, Farmer PE, Krakauer EL, De Lima L, Bhadelia A, Jiang Kwete X, et al. Alleviating the access abyss in palliative care and pain relief—an imperative of universal health coverage: the Lancet Commission report. Lancet. 2018;391(10128):1391–454. https://doi.org/10.1016/S0140-6736(17)32513-8
Holtmann M, Domagk D, Weber M, Moehler M, Pott G, Ramadori G, et al. Gastroenterologische Palliativmedizin. Z Gastroenterol. 2008;46:712–24. https://doi.org/10.1055/s-2008-1027378
Laugsand EA, Kaasa S, De Conno F, Hanks G, Klepstad P. Intensity and treatment of symptoms in 3030 palliative care patients: a cross-sectional survey of the EAPC Research Network. J Opioid Manag. 2009;5:11–21. https://doi.org/10.5055/jom.2009.0002
Arnstadt B, Allescher HD. Palliative endoscopy. Chirurg. 2022;93:310–22. https://doi.org/10.1007/s00104-021-01426-5
Teunissen SC, Wesker W, Kruitwagen C, De Haes HCJM, Voest EE, De Graeff A. Symptom prevalence in patients with incurable cancer: a systematic review. J Pain Symptom Manage. 2007;34:94–104. https://doi.org/10.1016/j.jpainsymman.2006.10.015
Schütte K, Weigt J, Meyer F, Malfertheiner P. Palliativtherapie im Grenzgebiet zwischen Gastroenterologie und (Viszeral-) Chirurgie. Zentralbl Chir. 2010;135:528–34. https://doi.org/10.1055/s-0030-1262702
Soliman YY, Kundranda M, Kachaamy T. Endoscopic palliative therapies for esophageal cancer. Gastrointest Endosc Clin N Am. 2024;34:91–109. https://doi.org/10.1016/j.giec.2023.07.003
Krouse RS. Malignant bowel obstruction. J Surg Oncol. 2019;120:74–7. https://doi.org/10.1002/jso.25451
Haluszka O. Palliative gastroenterology. Semin Oncol. 2005;32:174–8. https://doi.org/10.1053/j.seminoncol.2004.11.010
Gerson LB, Triadafilopoulos G. Palliative care in inflammatory bowel disease: an evidence-based approach. Inflamm Bowel Dis. 2000;6:228–43. https://doi.org/10.1097/00054725-200008000-00009
Rivet EB, Bohl JL, Al Yassin S, Bickston SJ. Palliative care in inflammatory bowel disease: a new partnership. Crohn’s Colitis 360. 2021;3:otab062. https://doi.org/10.1093/crocol/otab062
Scott LD. Quality medical care in gastroenterology: lessons from palliative medicine. Am J Gastroenterol. 2009;104:1352–5. https://doi.org/10.1038/ajg.2009.142
Drossman DA. Presidential address: gastrointestinal illness and the biopsychosocial model. Psychosom Med. 1998 May-Jun;60(3):258–67. https://doi.org/10.1097/00006842-199805000-00007
Feng L, Cai X, Zou Q, Peng Y, Xu L, Wang L, et al. Exploring the management and treatment of IBD from the perspective of psychological comorbidities. Ther Adv Gastroenterol. 2024 Oct 16;17:17562848241290685. https://doi.org/10.1177/17562848241290685
Langberg KM, Kapo JM, Taddei TH. Palliative care in decompensated cirrhosis: a review. Liver Int. 2018;38:768–75. https://doi.org/10.1111/liv.13620
Tandon P, Walling A, Patton H, Taddei T. AGA clinical practice update on palliative care management in cirrhosis: expert review. Clin Gastroenterol Hepatol. 2021;19:646–56.e3. https://doi.org/10.1016/j.cgh.2020.11.027
Shinall MC, Karlekar M, Martin S, Gatto CL, Misra S, Chung CY, et al. COMPASS: a pilot trial of an early palliative care intervention for patients with end-stage liver disease. J Pain Symptom Manage. 2019;58:614–22.e3. https://doi.org/10.1016/j.jpainsymman.2019.06.023
Lamba S, Murphy P, McVicker S, Harris Smith J, Mosenthal AC. Changing end-of-life care practice for liver transplant service patients: structured palliative care intervention in the surgical intensive care unit. J Pain Symptom Manage. 2012;44:508–19. https://doi.org/10.1016/j.jpainsymman.2011.10.018
Poonja Z, Brisebois A, Van Zanten SV, Tandon P, Meeberg G, Karvellas CJ. Patients with cirrhosis and denied liver transplants rarely receive adequate palliative care or appropriate management. Clin Gastroenterol Hepatol. 2014;12:692–8. https://doi.org/10.1016/j.cgh.2013.08.027
Kathpalia P, Smith A, Lai JC. Underutilization of palliative care services in the liver transplant population. World J Transplant. 2016;6:594–600. https://doi.org/10.5500/wjt.v6.i3.594
Morrison RS, Dietrich J, Ladwig S, Quill T, Sacco J, Tangeman J, et al. Palliative care consultation teams cut hospital costs for Medicaid beneficiaries. Health Aff (Millwood). 2011;30:454–63. https://doi.org/10.1377/hlthaff.2010.0929
Peng JK, Hepgul N, Higginson IJ, Gao W. Symptom prevalence and quality of life of patients with end-stage liver disease: a systematic review and meta-analysis. Palliat Med. 2019;33:24–36. https://doi.org/10.1177/0269216318807051
Will V, Rodrigues SG, Berzigotti A. Current treatment options of refractory ascites in liver cirrhosis: a systematic review and meta-analysis. Dig Liver Dis. 2022;54:1007–14. https://doi.org/10.1016/j.dld.2021.12.007
Shrestha D, Rathi S, Grover S, Taneja S, Duseja A, Chawla YK, et al. Factors affecting psychological burden on the informal caregiver of patients with cirrhosis: looking beyond the patient. J Clin Exp Hepatol. 2020;10:9–16. https://doi.org/10.1016/j.jceh.2019.06.002
Laube R, Sabih A, Strasser SI, Lim L, Cigolini M, Liu K. Palliative care in hepatocellular carcinoma. J Gastroenterol Hepatol. 2021;36:618–28. https://doi.org/10.1111/jgh.15169
Rush B, Walley KR, Celi LA, Rajoriya N, Brahmania M. Palliative care access for hospitalized patients with end‐stage liver disease across the United States. Hepatology. 2017;66:1585–91. https://doi.org/10.1002/hep.29297
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Brazilian Journal of Health Research

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The Revista Brasileira de Pesquisa em Saúde (RBPS) adopts the CC BY 4.0 license, which means that authors retain the copyright of the works they submit to the journal. Authors are responsible for declaring that their contribution is an original manuscript, that it has not been previously published, and that it is not under simultaneous review by another scientific journal. Upon submitting the manuscript, authors grant RBPS the exclusive right of first publication, subject to peer review.
Authors are permitted to enter into additional contracts for the non-exclusive distribution of the version published by RBPS (for example, in institutional repositories or as a book chapter), provided that due acknowledgment of authorship and of initial publication by RBPS is given. Authors are also encouraged to make their work available online (for example, in institutional repositories or on their personal pages) after its initial publication in the journal, with due acknowledgment of authorship and of the original publication by RBPS.
Accordingly, under the CC BY 4.0 license, readers have the right to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially;
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.