Correlation between ultrasonographic and cytopathological findings obtained by fine needle aspiration biopsy in the evaluation of thyroid nodules
DOI:
https://doi.org/10.47456/rbps.v26i1.51210Keywords:
Thyroid gland nodule, Thyroid gland, Thyroid Neoplasms, Needle biopsy, UltrasoundAbstract
Introduction: Thyroid nodules are prevalent, being identified by palpation in 4% to 7% of adult women and 1% of adult men and by ultrasonography (US) in 20% to 68% of patients. The incidence of thyroid cancer is approximately 24/100,000 population. It is important to define which nodule requires fine needle aspiration biopsy (FNAB) and which should be monitored. Objectives: To correlate the findings of the ultrasound aspects obtained by the TI-RADS classification with the data obtained by the cytopathological classification (Bethesda) of thyroid nodules that underwent FNAB. Methods: Retrospective, descriptive and cross-sectional study, in which the electronic medical records of ultrasound examination reports of patients with thyroid nodules and indication for FNAB were analyzed, in a clinic in Vitória/ES, between January/2023 and June/2023. Results: A total of 777 nodules in 659 patients (538 women and 121 men) were analyzed. The mean age was 51.94 years. Most nodules were larger than 1.0 cm and classified as TI-RADS 3 (74.5%), followed by classification 4 (14.5%), 2 (7.3%) and 5 (3.6%). An association was found between TI-RADS and the Bethesda classification (p<0.001). Most individuals with TI-RADS 2 or 3 presented Bethesda 2 results (91.2% and 82.6%, respectively). Of those classified as TI-RADS 4 and 5, most presented Bethesda III, IV, V or VI (45.1% and 81.4%). The proportion of malignancies among TI-RADS 2 was 1.7% and TI-RADS 3 was 10.0%. Conclusion: An association between TI-RADS and Bethesda was observed, confirming the importance of its use. The TI-RADS classification is appropriate to avoid unnecessary procedures.
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References
Graf H. Doença nodular de tireóide. Arquivos Brasileiros de Endocrinologia & Metabologia. 2004 Feb;48(1):93–104.
Rosário PW, Ward LS, Carvalho GA, Graf H, Maciel RMB, Maciel LMZ, et al. Thyroid nodules and differentiated thyroid cancer: update on the Brazilian consensus. Arquivos Brasileiros De Endocrinologia E Metabologia [Internet]. 2013 Jun 1;57(4):240–64.
Tappouni RR, Itri JN, McQueen TS, Lalwani N, Ou JJ. ACR TI-RADS: Pitfalls, Solutions, and Future Directions. RadioGraphics. 2019 Nov;39(7):2040–52.
Sandro Ceratti, Paula Prokopoff Giannini, Antenor R, Fermozelli O. Ultrasound-guided fine-needle aspiration of thyroid nodules: assessment of the ideal number of punctures. 2012 Jun 1;45(3):145–8.
Tessler FN, Middleton WD, Grant EG, Hoang JK, Berland LL, Teefey SA, et al. ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee. Journal of the American College of Radiology. 2017 May;14(5):587–95.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid: official journal of the American Thyroid Association [Internet]. 2016;26(1):1–133.
Furlanetto TW, S. Peccin, de A, dos A, dos S, Genro SK, et al. Prevalência de nódulos de tireóide detectados por ecografia em mulheres após os 40 anos. Revista da Associação Médica Brasileira. 2000 Oct 1;46(4):331–4.
Wildman-Tobriner B, Buda M, Hoang JK, Middleton WD, Thayer D, Short RG, et al. Using Artificial Intelligence to Revise ACR TI-RADS Risk Stratification of Thyroid Nodules: Diagnostic Accuracy and Utility. Radiology. 2019 Jul;292(1):112–9.
Rahal Junior A, Falsarella PM, Rocha RD, Lima JPBC, Iani MJ, Vieira FAC, et al. Correlation of Thyroid Imaging Reporting and Data System [TI-RADS] and fine needle aspiration: experience in 1,000 nodules. Einstein (São Paulo) [Internet]. 2016 Jun;14(2):119–23.
Nebu Abraham George, Suresh S, V. Jiji, Saxena R, Thomas S, Deepak Janardhan, et al. Correlation of TIRADS and Bethesda Scoring Systems with Final Histopathology of Thyroid Nodules – An Institutional Experience. Indian Journal of Otolaryngology and Head & Neck Surgery. 2021 Jan 21;74(S3):5753–8.
Gallardo JCA, Gallardo Quingatuña MÁ, Pérez Castillo R. Características ecográfica sugestivas de malignidad en nódulos quísticos del tiroides, Hospital “Hermanos Ameijeiras.” Revista Medica Sinergia. 2020 Mar 1;5(3):e277.
Grant EG, Tessler FN, Hoang JK, Langer JE, Beland MD, Berland LL, et al. Thyroid Ultrasound Reporting Lexicon: White Paper of the ACR Thyroid Imaging, Reporting and Data System (TIRADS) Committee. Journal of the American College of Radiology. 2015 Dec;12(12):1272–9.
Russ G, Bonnema Steen J, Erdogan M, Durante C, Ngu R, Leenhardt L. European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS. European Thyroid Journal. 2017;6(5):225–37.
Moon WJ, Baek JH, Jung SL, Kim DW, Kim EK, Kim JY, et al. Ultrasonography and the Ultrasound-Based Management of Thyroid Nodules: Consensus Statement and Recommendations. Korean Journal of Radiology. 2011;12(1):1.
Moon HJ, Kwak JY, Kim MJ, Son EJ, Kim EK. Can Vascularity at Power Doppler US Help Predict Thyroid Malignancy? Radiology. 2010 Apr;255(1):260–9.
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