Exophiala fungal arthritis in a patient with systemic lupus erythematosus

case report

Authors

  • Claudia Correa Ribeiro Universidade Federal do Espírito Santo
  • Rodrigo Mazzini Calmon Alves Hospital Universitário Cassiano Antônio Moraes
  • Luciana Batista da Silva Hospital Universitário Cassiano Antônio Moraes
  • Isac Ribeiro Moulaz Hospital Universitário Cassiano Antônio Moraes
  • Mariana de Oliveira Macabú Hospital Universitário Cassiano Antônio Moraes
  • Pietra Zava Lorencini Hospital Universitário Cassiano Antônio Moraes
  • Érica Vieira Serrano Hospital Universitário Cassiano Antônio Moraes
  • Lídia Balarini da Silva Hospital Universitário Cassiano Antônio Moraes
  • Renata Scarpat Careta Hospital Universitário Cassiano Antônio Moraes
  • Rafael Burgomeister Lourenço Hospital Universitário Cassiano Antônio Moraes
  • Fabíola Assad Antunes Hospital Universitário Cassiano Antônio Moraes
  • Ketty Lysie Libardi Lira Machado Universidade Federal do Espírito Santo
  • Valeria Valim Universidade Federal do Espírito Santo

DOI:

https://doi.org/10.47456/rbps.v26isupl_3.08

Keywords:

Septic arthritis, Immunosuppression, Phaeohyphomycosis, Exophiala

Abstract

Introduction: Fungi of the genus Exophiala sp are found in soil and organic matter. They have low virulence and are generally symptomatic in immunosuppressed individuals. The main clinical manifestations are cutaneous or subcutaneous alterations, with joint involvement being rare. Case report: We report a case of a patient with Systemic Lupus Erythematosus (SLE), on immunosuppressive therapy, presenting with chronic monoarthritis of the left wrist, with a diagnosis of septic arthritis caused by a fungus of the genus Exophiala sp, evidenced by histopathological analysis, culture and colony micromorphology of the synovial fluid. Conclusion: This is the first case reported in the literature of a SLE patient with joint involvement caused by Exophiala sp. Histopathology and culture are the gold standard for the precise diagnosis of fungal monoarthritis. Early diagnosis is essential due to the risk of chronicity and poor joint prognosis in patients who do not receive specific treatment.

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Published

2025-02-11

Issue

Section

Relato de Caso

How to Cite

1.
Exophiala fungal arthritis in a patient with systemic lupus erythematosus: case report . RBPS [Internet]. 2025 Feb. 11 [cited 2026 Feb. 24];26(supl_3):61-6. Available from: https://periodicos.ufes.br/rbps/article/view/47627

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