Evaluation of intestinal dysbiosis and associated health factors in vegetarian individuals
DOI:
https://doi.org/10.47456/rbps.v26i1.41946Keywords:
Dysbiosis, Vegetarian Diet, Intestinal microbiotaAbstract
Introduction: The composition of the intestinal microbiota is closely related to the lifestyle and clinical conditions of the individual, and the type of diet may be a causal factor of dysbiosis. Objective: To evaluate the health factors associated with intestinal dysbiosis in vegetarian individuals. Methods: Cross-sectional observational study with a convenience sample, composed of vegetarian individuals aged ≥ 18 and < 60 years, of both sexes. The collection occurred with an online questionnaire. The outcome of intestinal dysbiosis was investigated using the Metabolic Screening Questionnaire (QRM), in addition, to which sociodemographic, anthropometric, behavioral, stool consistency (Bristol Scale) and biochemical variables were analyzed. Possible associations between the variables and the outcome were also analyzed. The level of statistical significance adopted was 5%. Results: There was a low prevalence of intestinal dysbiosis (15.9%). Associations were found between the following variables and the outcome: female gender (p=0.029), mild diarrhea parameter on the Bristol Scale (p≤0.0001), and severe Vitamin D deficiency (p=0.035). Conclusion: The vegetarian eating pattern can be a protective factor against intestinal dysbiosis, given the low prevalence found, in addition to this there is an association with Vitamin D deficiency, gender and the presence of diarrhea.
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References
Reis AC et al. Sinais e sintomas sugestivos de disbiose intestinal na população brasileira: uma revisão de literatura. Research, Society and Development, 2022;11(9):e56111932094.
Weiss GA, Hennet T. Mechanisms and consequences of intestinal dysbiosis. Cellular and Molecular Life Sciences. 2017;74(16):2959-77.
Lee CJ, Sears CL, Maruthur N. Gut microbiome and its role in obesity and insulin resistance. Annals of the New York Academy of Sciences. 2020;1461(1):37-52.
Hiel S, Bindels LB, Pachikian BD, Kalala G, Broers V, Zamariola G et al. Effects of a diet based on inulin-rich vegetables on gut health and nutritional behavior in healthy humans. The American journal of clinical nutrition, 2019;109(6):1683-95.
Kahleova H, Petersen KF, Shulman GI, Alwarith J, Rembert E, Tura A et al. Effect of a low-fat vegan diet on body weight, insulin sensitivity, postprandial metabolism, and intramyocellular and hepatocellular lipid levels in overweight adults: a randomized clinical trial. JAMA Network Open, 2020;3(11):e2025454.
Moszak M, Szulińska M, Bogdański P. You are what you eat —the relationship between diet, microbiota, and metabolic disorders— A review. Nutrients, 2020;12(4):1096.
Abu‐Ghazaleh N, Chua WJ, Gopalan V. Intestinal microbiota and its association with colon cancer and red/processed meat consumption. Journal Gastroenterology hepatology, 2021;36(1):75-88.
Da Silva FG et al. Os benefícios da dieta vegetariana nas dislipidemias. Recima 21: Rev Científica Multidisciplinar, 2022;3(11):e3112071.
Inteligência I. Pesquisa de opinião pública sobre vegetarianismo. São Paulo: Sociedade Vegetariana Brasileira. 2018.
Hargreaves SM, Araújo WMC, Nakano EY, Zandonadi RP. Brazilian vegetarians diet quality markers and comparison with the general population: a nationwide cross-sectional study. PloS One, 2020;15(5):e0232954.
Willett W, Rockström J, Loken B, Springmann M, Lang T, Vermeulen S et al. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. The Lancet, 2019;393(10170):447-92.
World Health Organization. Obesity: preventing and managing the global epidemic: report of a WHO consultation on obesity, Geneva, 3-5 June 1997. World Health Organization; 1998.
World Health Organization. WHO guidelines on physical activity and sedentary behaviour. 2020.
Ribas Filho D, Almeida CAN, Oliveira Filho AE. Posicionamento atual sobre vitamina D na prática clínica: posicionamento da Associação Brasileira de Nutrologia (Abran). International Journal of Nutrology, 2019;12(3):82-96.
Faludi AA, Izar MCO, Saraiva JFK, Chacra APM, Bianco HT, Afiune A et al. Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose, 2017. Arquivos Brasileiros de Cardiologia, 2017;109:1-76.
Oliveira JEP, Vencio S. Diretrizes da Sociedade Brasileira de Diabetes 2017-2018. São Paulo: Editora Clannad, 2017;91.
Blake M, Raker J, Whelan K. Validity and reliability of the Bristol Stool Form Scale in healthy adults and patients with diarrhoea‐predominant irritable bowel syndrome. Alimentary Pharmacology & Therapeutics, 2016;44(7):693-703.
Vieira GC, Santos Castro FF. Aspectos fisiopatológicos da disbiose intestinal em estudantes de uma instituição de ensino privada do Distrito Federal. Revista Eletrônica Acervo Saúde, 2021;13(1):e5249.
Dagostin B, Santos Guellere ML, Gesuino DB, Madeira K, Santos HO, Luciano TF. Sinais e sintomas de hipersensibilidades alimentares entre indivíduos vegetarianos vs. onívoros. RBONE: Rev Brasil Obesidade, Nutrição Emagrecimento, 2020;14(87):540-9.
Sakkas H, Bozidis P, Touzios C, Kolios D, Athanasiou G, Athanasopoulou E et al. Nutritional status and the influence of the vegan diet on the gut microbiota and human health. Medicina, 2020;56(2):88.
Tomova A, Bukovsky I, Rembert E, Yonas W, Alwarith J, Barnard ND, Kahleova H. The effects of vegetarian and vegan diets on gut microbiota. Front. Nutr, 2019;6(1):47.
Kahleova H, Dort S, Holubkov R, Barnard ND. A plant-based high-carbohydrate, low-fat diet in overweight individuals in a 16-week randomized clinical trial: the role of carbohydrates. Nutrients, 2018;10(9):1302.
Naderpoor N, Mousa A, Arango FGL, Barrett HL, Dekker Nitert M, Courten B. Effect of vitamin D supplementation on faecal microbiota: a randomised clinical trial. Nutrients, 2019;11(12):2888.
Singh P, Rawat A, Alwakeel M, Sharif E, Al Khodor S. The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals. Scientific reports, 2020;10(1):1-14.
Kanhere M, He J, Chassaing B, Ziegler TR, Alvarez JA, Ivie EA et al. Bolus weekly vitamin D3 supplementation impacts gut and airway microbiota in adults with cystic fibrosis: a double-blind, randomized, placebo-controlled clinical trial. J Clinical Endocrinology Metabolism, 2018;103(2):564-74.
Malaguarnera, L. Vitamin D and microbiota: Two sides of the same coin in the immunomodulatory aspects. International Immunopharmacology, 2020;79(1):106-112.
Vandenplas Y, Huys G, Daube G. Probióticos: informações atualizadas. J Pediatria, 2015;91:6-21.
Li Y, Xia S, Jiang X, Feng C, Gong S, Ma J et al. Gut microbiota and diarrhea: an updated review. Front. Cell. Infect. Microbiol, 2021;11:625210.
Insenser M, Murri M, Del Campo R, Martinez-Garcia MA, Fernandez-Duran E, Escobar-Morreale HF. Gut microbiota and the polycystic ovary syndrome: influence of sex, sex hormones, and obesity. J Clinical Endocrinology Metabolism, 2018;103(7):2552-62.
Siddiqui R, Makhlouf Z, Alharbi AM, Alfahemi H, Khan NA. The gut microbiome and female health. Biology, 2022;11(1):1683
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