Whipple’s disease and risk factor in three case reports

Abstract

Introduction: Whipple’s Disease is a chronic infection disease caused by the bacterium Tropheryma whipplei and is characterized by diarrhea, arthralgia, weight loss and neurological disorders. The infection occurs more frequently in immunosuppressed patients. Case report: Whipple’s Disease was diagnosed in three Caucasian mans. Two with alcohol dependence history, one of them with hepatic cirrhosis and another was a sewage drainage worker. The third patient was who have no obvious risk factor Identify immunosuppressive factors and repetitive stools contact can help in the diagnosis. Conclusion: Whipple’s Disease, being rare and with variable symptomatology, needs medical suspicion to diagnose early provide treatment reducing morbimortality and neurological sequelae.