Paracoccidioidomicose juvenil disseminada evoluindo com hipertensão portal: um relato de caso
DOI:
https://doi.org/10.47456/rbps.v26isupl_1.44396Keywords:
Paracoccidioidomicose, Hipertensão portal, ParacoccidioidesAbstract
Introdução: A paracoccidioidomicose juvenil (PCM), doença causada pelos fungos do gênero Paracoccidioides, exige alta suspeição clínica, já que uma gama de diagnósticos diferenciais é possível. Relato de caso: Neste relato é descrito um paciente com diagnóstico de PCM forma juvenil que devido à baixa adesão ao tratamento evoluiu em oito anos para uma invasão fúngica mais extensa, ocasionando hipertensão portal por trombose de veia porta. Esta é uma manifestação clínica rara e grave. Conclusão: Foram identificados somente seis relatos similares na literatura médica, por meio de busca nas bases de dados das plataformas Pubmed e Scielo.
Downloads
References
Peçanha PM, Peçanha-Pietrobom PM, Grão-Velloso TR, Rosa Júnior M, Falqueto A, Gonçalves SS. Paracoccidioidomycosis: What We Know and What Is New in Epidemiology, Diagno¬sis, and Treatment. J Fungi (Basel). 2022 Oct 18;8(10):1098. doi: 10.3390/jof8101098.
Shikanai-Yasuda MA, Mendes RP, Colombo AL, Queiroz-Telles F, Kono ASG, Paniago AMM, et al. Brazilian guidelines for the clinical management of paracoccidioidomycosis. Rev Soc Bras Med Trop. 2017 Sep-Oct;50(5):715-740. doi: 10.1590/0037-8682- 0230-2017.
Peçanha PM, Batista Ferreira ME, Massaroni Peçanha MA, Schmidt EB, Lamas de Araújo M, Zanotti RL, et al. Paracoccidi¬oidomycosis: Epidemiological and Clinical Aspects in 546 Cases Studied in the State of Espírito Santo, Brazil. Am J Trop Med Hyg. 2017 Sep;97(3):836-844. doi: 10.4269/ajtmh.16-0790.
Macedo PM, Almeida-Paes R, Freitas DFS, Brito-Santos F, Figue¬iredo-Carvalho MHG, Soares JCA, et al. Hepatic Disease with Portal Hypertension and Acute Juvenile Paracoccidioidomyco¬sis: A Report of Two Cases and Literature Review. Mycopathol. 2017 Oct;182(9-10):915-919. doi:10.1007/s11046-017-0152-6.
Marchiotti MC, Cabral JN, Zangirolami JW, Bressa, JAN. Paracoccidioidomicose subaguda septicêmica levando a infarto esplênico e trombose de veia porta no indivíduo imunocompe¬tente: a propósito de um caso. Braz J Infect Dis. 2021 25(S1), 101443. doi:10.1016/j.bjid.2020.101443
Stringuini FA, Naback PO, Araújo LF, Lima RB, Martins CJ. Severe paracoccidioidomycosis, with a fatal outcome and inci¬dence related to an environmental event. Br J Dermatol. 2023 98(1), 133-137. doi:10.1016/j.abd.2021.12.006
Rocha FL, Araújo TD. Acute paracoccidioidomycosis in a 40-year-old man: a case report and literature review. Myco¬pathol. 2017 Dec;182(11-12):1095-1099. doi: 10.1007/s11046-017- 0196-7.
Bermudes FT, Pareja HBJ, Sannino CP, Dias LVP, Saka¬moto MNG, Saab J, et al. Paracoccidioidomycosis causing Cholestatic Syndrome: a case report. Braz. J. Hea. Rev. 2022 Oct.13;5(5):20561-73. doi:10.34119/bjhrv5n5-223.
Filho FB, Sgarbi I, Domingos SFS, Sampaio RC, Queiroz RM, Fonseca SNS, Hay RJ, Towersey L. Acute paracoccidioidomy¬cosis with duodenal and cutaneous involvement and obstruc¬tive jaundice. Med Mycol Case Rep. 2018 Jan 12;20:21-25. doi: 10.1016/j.mmcr.2018.01.005.
Cazzo E, Ferrer JA, Chaim EA. Obstructive jaundice second¬ary to paracoccidioidomycosis. Trop Gastroenterol. 2015 Jan- Mar;36(1):46-7. doi: 10.7869/tg.244.
Savarese LG, Monsignore LM, Hernandes MA, Martinez R, Nogueira-Barbosa MH. Magnetic resonance imaging find¬ings of paracoccidioidomycosis in the musculoskeletal system. Trop Med Int Health. 2015 Oct;20(10):1346-54. doi: 10.1111/ tmi.12552.
Rodrigues FB, Machado AA, Martinez R. Paracoccidioidomyco¬sis epidemiological features of a 1,000- cases series from a hype¬rendemic area on the Southeast of Brazil. Am J Trop Med Hyg. 2011;85(3):546–50. doi:10.4269/ajtmh.2011.11-0084.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Brazilian Journal of Health Research

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors and reviewers must disclose any financial, professional, or personal conflicts of interest that could influence the results or interpretations of the work. This information will be treated confidentially and disclosed only as necessary to ensure transparency and impartiality in the publication process.
Copyright
RBPS adheres to the CC-BY-NC 4.0 license, meaning authors retain copyright of their work submitted to the journal.
- Originality Declaration: Authors must declare that their submission is original, has not been previously published, and is not under review elsewhere.
- Publication Rights: Upon submission, authors grant RBPS the exclusive right of first publication, subject to peer review.
- Additional Agreements: Authors may enter into non-exclusive agreements for the distribution of the RBPS-published version (e.g., in institutional repositories or as book chapters), provided the original authorship and publication by RBPS are acknowledged.
Authors are encouraged to share their work online (e.g., institutional repositories or personal websites) after initial publication in RBPS, with appropriate citation of authorship and original publication.
Under the CC-BY-NC 4.0 license, readers have the rights to:
- Share: Copy and redistribute the material in any medium or format.
- Adapt: Remix, transform, and build upon the material.
These rights cannot be revoked, provided the following terms are met:
- Attribution: Proper credit must be given, a link to the license provided, and any changes clearly indicated.
- Non-Commercial: The material cannot be used for commercial purposes.
- No Additional Restrictions: No legal or technological measures may be applied to restrict others from doing anything the license permits.