Peritoneal tuberculosis
case report
DOI:
https://doi.org/10.47456/rbps.v26isupl_3.12Keywords:
Peritoneal tuberculosis, Mycobacterium tuberculosis, Ascites, LaparoscopyAbstract
Introduction: Tuberculosis is an infectious, transmissible disease caused by the bacillus Mycobacterium tuberculosis, with the lungs being the most affected organ. Abdominal tuberculosis is the sixth most affected extrapulmonary site, affecting the gastrointestinal tract, peritoneum or mesenteric lymph nodes. Peritoneal tuberculosis affects both sexes and is related to low socioeconomic status, crowding and is associated with other comorbidities. It is an insidious disease. The main signs and symptoms are abdominal pain, ascites, weight loss and fever. Objective: To report a case of peritoneal tuberculosis, a rare and sometimes underdiagnosed disease, to assist health professionals in early diagnosis and treatment. Case report: A 60-year-old man, hypertensive and ex-smoker for 8 days, presented with diffuse abdominal pain and increased abdominal volume. Abdominal physical examination revealed mobile dullness. Diagnostic paracentesis revealed hypercellular ascitic fluid with a predominance of mononuclear cells, with a serum-ascites albumin gradient <1.1. Abdominal tomography showed small nodular thickenings with contrast enhancement scattered throughout the peritoneum. Diagnostic laparoscopy for peritoneal biopsy revealed multiple rice-grain nodules that were biopsied and histopathologically concluded as chronic granulomatous tuberculoid necrotizing inflammation. Conclusion: Peritoneal tuberculosis is a rare disease with subacute presentation and nonspecific symptoms. The gold standard for diagnosis is peritoneal biopsy, preferably by laparoscopy with subsequent histological or microbiological confirmation. The treatment of peritoneal tuberculosis does not differ from the treatment of pulmonary tuberculosis. Delayed diagnosis and treatment are one of the main factors of morbidity and mortality, therefore early diagnosis and treatment are important.
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References
1. World Health Organization. Global tuberculosis report 2021. Geneva: 2021.
2. Dineeen P, Homan WP, Grafe WR. Tuberculous peritonitis: 43 years' expereince in diagnosis and treatment. Ann Surg. 1976 Dec;184(6):717-22.
3. Agência.Fiocruz.br [homepage na internet]. Fiocruz, Saúde e ciência para todos. Tuberculose. (acesso em 10 abr. 2023) Disponível em: https://agencia.fiocruz.br/glossario-tuberculose.
4. Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis. Brasil Livre da Tuberculose: Plano Nacional pelo Fim da Tuberculose como Problema de Saúde Pública: estratégias para 2021-2025. Brasília: Ministério da Saúde, 2021. (acesso em 15 abr.2023). Disponível em: https://bvsms.saude.gov.br/bvs/publicacoes/brasil_livre_tuberculose_plano_nacional.pdf.
5. Brasil, Ministério da Saúde. Secretaria de Vigilância em Saúde. Março de 2022. Boletim epidemiológico, Tuberculose 2022. (acesso em 15 abr. 2023) Disponível em: https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/especiais/2022/boletim-epidemiologico-de-tuberculose-numero-especial-marco-2022.pdf.
6. Wu DC, Averbukh LD, Wu GY. Diagnostic and Therapeutic Strategies for Peritoneal Tuberculosis: A Review. J Clin Transl Hepatol. 2019 Jun 28;7(2):140-148.
7. Vaid U, Kane GC. Tuberculous Peritonitis. Microbiol Spectr. 2017 Jan;5(1).
8. Sanai FM, Bzeizi KI. Systematic review: tuberculous peritonitis--presenting features, diagnostic strategies and treatment. Aliment Pharmacol Ther. 2005 Oct 15;22(8):685-700.
9. Chow KM, Chow VC, Hung LC, Wong SM, Szeto CC. Tuberculous peritonitis-associated mortality is high among patients waiting for the results of mycobacterial cultures of ascitic fluid samples. Clin Infect Dis. 2002 Aug 15;35(4):409-13.
10. Manohar A, Simjee AE, Haffejee AA, Pettengell KE. Symptoms and investigative findings in 145 patients with tuberculous peritonitis diagnosed by peritoneoscopy and biopsy over a five-year period. Gut. 1990 Oct;31(10):1130-2.
11. Demir K, Okten A, Kaymakoglu S, Dincer D, Besisik F, Cevikbas U, et.al. Tuberculous peritonitis--reports of 26 cases, detailing diagnostic and therapeutic problems. Eur J Gastroenterol Hepatol. 2001 May;13(5):581-5.
12. Abdelaal A, Alfkey R, Abdelaziem S, Abunada M, Alfaky A, Ibrahim WH, et.al. Role of laparoscopic peritoneal biopsy in the diagnosis of peritoneal tuberculosis. A seven-year experience. Chirurgia (Bucur). 2014 May-Jun;109(3):330-4.
13. Huang B, Cui DJ, Ren Y, Han B, Yang P, Zhao X. Comparison between laparoscopy and laboratory tests for the diagnosis of tuberculous peritonitis. Turk J Med Sci. 2018 Aug 16;48(4):711-715.
14. Vyravanathan S, Jeyarajah R. Tuberculous peritonitis: a review of thirty-five cases. Postgrad Med J. 1980 Sep;56(659):649-51.
15. Debi U, Ravisankar V, Prasad KK, Sinha SK, Sharma AK. Abdominal tuberculosis of the gastrointestinal tract: revisited. World J Gastroenterol. 2014 Oct 28;20(40):14831-40.
16. Maranhão BHF, Silva Junior CT, Chibante AMS, Cardoso GP. Dosagem de proteínas totais e desidrogenase lática para o diagnóstico de transudato e exsudato pleurais: redefinindo o critério clássico com uma nova abordagem estatística. J.bras.pneumol. 2010 Jul-Ago 36(4): 468-474.
17. Koff A, Azar MM. Diagnosing peritoneal tuberculosis. BMJ Case Rep. 2020 Feb 6;13(2):e233131.
18. Pahal P, Sharma S. PPD Skin Test. 2022 Jan 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022.
19. Gilani B, Sergent SR. Interferon Test. 2022 Jul 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022.
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