Blockchain applied in healthcare: a bibliometric review

Authors

  • Barbara Emanuelle Cavalcante dos Santos Universidade Federal do Recôncavo da Bahia
  • Fernanda Alves da Silva Instituto Federal de Educação, Ciência e tecnologia de São Paulo
  • Andressa Clara Barbosa de Araújo Universidade Federal do Recôncavo da Bahia https://orcid.org/0000-0002-1734-506X
  • Cristiane Agra Pimentel Universidade Federal do Recôncavo da Bahia https://orcid.org/0000-0001-9939-0309

DOI:

https://doi.org/10.47456/bjpe.v10i3.45125

Keywords:

Blockchain, Bibliometric Review, health

Abstract

The healthcare industry has taken advantage of the introduction of digital technologies. The application of Blockchain in healthcare has enormous disruptive potential, as it has the ability to provide greater reliability in the storage of medical records and reduce the risk of tampering. This research aims to present a bibliometric study on Blockchain in health, aiming to identify the main regions in the world that study the subject, the educational institutions that have published the most on the subject and its most recurrent applications. As a methodology, a systematic exploratory procedure was used to extract works from Scopus and Web of Science (WoS) databases, with qualitative analysis facilitated by Microsoft Excel software, where it was possible to analyze the available literature on Blockchain in health. A total of 397 studies out of 967 were selected, being these, 311 articles from Scopus and 86 from WoS. The study revealed that China is the country that has published the most on the subject with 70 articles. In relation to teaching institutions and/or research groups, the IEEE stands out with 8 publications. Finally, Blockchain applications in health, after the standardization carried out, highlight the Medical Data Management with 118 records in the analyzed databases. This bibliometric review shows that there is a lack of studies in Brazil, on the other hand, it shows to be very promising for the health area.

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Author Biographies

Barbara Emanuelle Cavalcante dos Santos, Universidade Federal do Recôncavo da Bahia

I am a professional with a background in Energy and Sustainability, complemented by my current degree in Production Engineering. Throughout my journey, I accumulated significant experiences, including leadership in the Production Engineering area and later the role of Financial Administrative Director at ENGTEMP JR.
My trajectory also involved voluntary participation and as a scholarship holder in the Lean Healthcare scientific initiation project, publication of articles and patented educational games, as well as participation in national congresses, all contributing to my professional development and connections in the area.

Fernanda Alves da Silva, Instituto Federal de Educação, Ciência e tecnologia de São Paulo

Graduating in Production Engineering at the Federal Institute of Education, Science and Technology of São Paul (IFSP - 2022). She was an intern at the Health Department of the city of Barueri, a municipality in the state of São Paulo (2016-2017). Scholarship in Scientific Initiations in the areas of Data Mining applied to the area of ​​education (2019) and Lean Healthcare (2020). Founder and Vice-President of ProVale Jr (2020 - 2021). Volunteer in the Lean Healthcare UFRB research group (2022) and teaching fellow, intuiting herself in the construction of materials to promote knowledge in Lean Healthcare. Publication of articles in congresses, symposiums and international journals in the areas of Supply Chain, Operational Research, Automation and Control, Applied Physics, Lean Healthcare, Education. Green Belt in Lean Six Sigma and Hospital Pricing Intern at Dasa with experience in pricing and process automation projects (2022).

Andressa Clara Barbosa de Araújo, Universidade Federal do Recôncavo da Bahia

Master's student in the Industrial Engineering Program (MPEI-P) at UFBA, researching in the area of ​​Digital Twin.
• Bachelor's degree in Production Engineering from the Federal University of Recôncavo da Bahia (2023.1).
• Bachelor in Interdisciplinary in Energy and Sustainability from the Federal University of Recôncavo da Bahia - UFRB (2022.2).
• Lean Healthcare Researcher at UFRB (2021-2024)
• Best course completion work in production engineering of 2023 (Abepro Award).
• 2 computer programs registered by INPI with support from UFRB.
• 3 games registered as Industrial Design and awarded with UFRB inventor recognition.
• Experience in the area of ​​Lean Healthcare and continuous improvement in health, and as a mobilizer and facilitator of workshops with young people and adults in the environmental area.

Cristiane Agra Pimentel, Universidade Federal do Recôncavo da Bahia

Currently a professor at the Federal University of Recôncavo da Bahia (UFRB) in Feira de Santana on the Production Engineering course, senior member of IEEE and participant in the professional master's degree at UFBA. She has 12 years of experience in the metallurgical industrial area. She has expertise developed in the areas of quality, production system (lean), audits and certifications. Internal and external auditor of the Integrated Management System (ISO 9001, ISO 14001 and ISO IEC 17025) and Green Belt. During her master's degree she worked with the implementation of ISO standards in the public service, highlighting the accreditation of the Biomaterials laboratory of the Northeast CERTBIO in the ISO / IEC 17025 standard, and during her doctorate she worked with the development of materials for application as biomaterials. She currently leads the Lean Healthcare research project with a focus on the health area at BA and the Impacts of AI on education, in addition to working on issues related to female performance in exact sciences. Conducting the Digital Twin project in cooperation with CEPEDI de Ilhéus. Recipient of the 2021 IEEE Undergraduate Teaching Award, Honorable Mention of the IEEE WIE 2021 and 2022- Inspiring Member of the Year Award and 2021 Outstanding Branch Counselor Branch Chapter Advisor Award. As of 2024, she is a member of the IEEE R9 Industry Engagement Committee and is Vice Chair of the WIE northeast section.

References

Abijaude, J., Serra, H., Barretto, R., Bezerra, A., Sobreira, P., & Greve, F. (2021). Internet das coisas, blockchain e contratos inteligentes aplicados à saúde. Sociedade Brasileira de Computação.

Alonso, S. G., Arambarri, J., López-Coronado, M., & De La Torre Díez, I. (2019). Proposing new blockchain challenges in ehealth. Journal of medical systems, 43(3), 1-7. https://doi.org/10.1007/s10916-019-1195-7

Ammouial, D. E. (2017). Blockchain for Business. http://dx.doi.org/10.18235/0003747

Antony, J., Snee, R., & Hoerl, R. (2017). Lean Six Sigma: yesterday, today and tomorrow. International Journal of Quality & Reliability Management, 34(7), 1073-1093. https://doi.org/10.1108/IJQRM-03-2016-0035

Attademo, C. V., Carneiro, H. Y. A., De Andrade, H. P., & Mancia, J. R. (2021). Impacto do big data na implementação de políticas públicas voltadas à saúde. Vita et Sanitas, 15(2), 41-52.

Baz, M., Khatri, S., Baz, A., Alhakami, H., Agrawal, A., & Khan, R. A. (2022). Blockchain and artificial intelligence applications to defeat COVID-19 pandemic. Computer Systems Science and Engineering, 691-702. http://dx.doi.org/10.32604/csse.2022.019079?

Begoli, E. & Horey, J. (2012, August). Design principles for effective knowledge discovery from big data. In 2012 Joint Working IEEE/IFIP Conference on Software Architecture and European Conference on Software Architecture (pp. 215-218). IEEE.

Bell, L., Buchanan, W. J., Cameron, J., & Lo, O. (2018). Applications of blockchain within healthcare. Blockchain in healthcare today. Recuperado de http://researchrepository.napier.ac.uk/Output/1191195

Bigini, G., Freschi, V., & Lattanzi, E. (2020). A review on blockchain for the internet of medical things: Definitions, challenges, applications, and vision. Future Internet, 12(12), 208. https://doi.org/10.3390/fi12120208

Bovério, M. A. & Da Silva, V. A. F. (2018). Blockchain: uma tecnologia além da criptomoeda virtual. Revista Interface Tecnológica, 15(1), 109-121. https://doi.org/10.31510/infa.v15i1.326

Bragazzi, N. L., DAI, H., Damiani, G., Behzadifar, M., Martini, M., & WU, J. (2020). How big data and artificial intelligence can help better manage the COVID-19 pandemic. International journal of environmental research and public health, 17(9), 3176. https://doi.org/10.3390/ijerph17093176

Buterin, V. (2015). On public and private blockchains. Ethereum blog, 7(1). https://doi.org/10.4337/9781784717766.00019

Camara, M. A. A., Lins, G. H. A., De Oliveira, F. H. C., Camelo, E. M. A., & De Medeiros, N. R. F. C. (2021). Internet das Coisas e blockchain no Sistema Único de Saúde: a proteção dos dados sensíveis diante da Lei Geral de Proteção de Dados. Cadernos Ibero-Americanos de Direito Sanitário, 10(1), 93-112. https://orcid.org/0000-0002-7663-3029

Cheng, A. S., Guan, Q., Su, Y., Zhou, P., & Zeng, Y. (2021). Integration of Machine Learning and Blockchain Technology in the Healthcare Field: A Literature Review and Implications for Cancer Care. Asia-Pacific Journal of Oncology Nursing, 8(6), 720-724. https://doi.org/10.4103/apjon.apjon-2140

Chen, Z., Xu, W., Wang, B., & YU, H. (2021). A blockchain-based preserving and sharing system for medical data privacy. Future Generation Computer Systems, 124, 338-350. https://doi.org/10.1016/j.future.2021.05.02

Chenthara, S., Ahmed, K., Wang, H., Whittaker, & F. Chen, Z., 2020 Healthchain: uma nova estrutura sobre preservação da privacidade de registros eletrônicos de saúde usando a tecnologia blockchain. PloS One 15. https://doi.org/10.1371/journal.pone.0243043

Cobianchi, L., Dal Mas, F., & Angelos, P. (2021). One size does not fit all–translating knowledge to bridge the gaps to diversity and inclusion of surgical teams. Annals of Surgery, 273(2), e34-e36. https://doi.org/10.1097/SLA.0000000000004604

Cobianchi, L., Dal Mas, F., Massaro, M., Bednarova, R., Biancuzzi, H., Filisetti, C., Barcellini, A., Orlandi, E., Miceli, L., & Angelos, P. , 2021b. Hand in hand: a multisectoral approach to surgical care co-production. Sou. J. Surg. https://doi.org/10.1016/j.amjsurg.2021.07.053

Coutinho, L. R., Neves, H. P. O. D. E., & Lopes, L. C. (2021). Approaches to cloud computing: a brief review on security and privacy applied to e-health in the context of the Conect SUS Program and the National Health Data Network (RNDS).Brazilian Journal of Development, 7(4), 35152-35170. https://doi.org/10.34117/bjdv7n4-127

Da Conceição, A. F., Rocha, V. M., & De Paula, R. F. (2019). Blockchain e Aplicações em Saúde. Sociedade Brasileira de Computação.

Dabbagh, M., Sookhak, M., & Safa, N. S. (2019). The evolution of blockchain: A bibliometric study. Ieee Access, 7, 19212-19221. https://doi.org/10.1109/ACCESS.2019.2895646

De Koning, H., Verver, J. P., van den Heuvel, J., Bisgaard, S., & Does, R. J. (2006). Lean six sigma in healthcare. The Journal for Healthcare Quality (JHQ), 28(2), 4-11. https://doi.org/10.1111/j.1945-1474.2006.tb00596.x

De Lucena, A. U. D., & Henriques, M. A. A. (2016). Estudo de arquiteturas dos blockchains de Bitcoin e Ethereum. IX Encontro de Alunos e Docentes do DCA/FEEC/UNICAMP, 9, 29-30.

De Souza, B. S. (2021). PEP+: A Blockchain Model for Syphilis Case Management.

Del Grossi, V. C. D. (2020). O BRICS e as iniciativas em ciência, tecnologia e inovação pós-cúpula de Joanesburgo. Novum Jus, 14(1), 137-164. https://doi.org/10.14718/novumjus.2020.14.1.6

Dinh, T. T. A., Liu, R., Zhang, M., Chen, G., Ooi, B. C., & Wang, J. (2018) Untangling Blockchain: A Data Processing View of Blockchain Systems. IEEE Transactions on Knowledge and Data Engineering, 30(7), 1366-1385. https://doi.org/10.1109/TKDE.2017.2781227

El-Gazzar, R., & Stendal, K. (2020). Blockchain in health care: hope or hype?. Journal of Medical Internet Research, 22(7), e17199. Recuperado de https://www.jmir.org/2020/7/e17199/

Elmar, K., Marti-Bonmati, L., Brady, A. P., & Desouza, N. M. (2021). ESR white paper: blockchain and medical imaging. Insights into Imaging, 12(1). https://doi.org/10.1186/s13244-021-01029-y

E. V., & Antony, J. (2019). Application of Lean Six Sigma in IT support services–a case study. The TQM Journal, 31(3), 417-435. doi: 10.1108/TQM-11- 2018-0168

Fernández-Caramés, T. M., Froiz-Míguez, I., Blanco-Novoa, O., & Fraga-Lamas, P. (2019). Enabling the internet of mobile crowdsourcing health things: A mobile fog computing, blockchain and IoT based continuous glucose monitoring system for diabetes mellitus research and care. Sensors, 19(15), 3319. https://doi.org/10.3390/s19153319

Fusco, A., Dicuonzo, G., Dell'attI, V., & Tatullo, M., 2020. Blockchain na área da saúde: insights sobre o COVID-19. Int. J. Ambiente. Res. Publ. Saúde 17, 1-12. https://doi.org/10.3390/ijerph17197167

Gates, M. (2017). Blockchain: Ultimate guide to understanding blockchain, bitcoin, cryptocurrencies, smart contracts and the future of money (Vol. 125). Scotts Valley: CreateSpace Independent Publishing Platform.

Gaynor, M., Tuttle-Newhall, J., Parker, J., Patel, A., & Tang, C. (2020). Adoption of blockchain in health care. Journal of medical Internet research, 22(9), e17423. https://doi.org/10.2196/17423

Giamberardino Filho, D. D. (2017). O Sistema Único de Saúde e as filas de espera para cirurgias eletivas. Arquivos do CRM-PR, 34(135). Recuperado de https://portal.cfm.org.br/artigos/o-sistema-unico-de-saude-e-as-filas-de-espera-para-cirurgias-eletivas

Gil, A. C. (2008). Como elaborar projetos de pesquisa. São Paulo: Atlas, 2010. LACOMBE, FJM/GILBERTO. LJH Administration: Principles and trends. rev. and updated. São Paulo: Saraiva.

Griggs, K. N., Ossipova, O., Kohlios, C. P., Baccarini, A.N., HOWson, E. A., & Hayajneh T. Sistema blockchain de saúde usando contratos inteligentes para monitoramento remoto automatizado seguro de pacientes. J Med Syst. 2018 Jun 6;42(7):130. https://doi.org/10.1007/s10916-018-0982-x

Huang, H., Zhu, P., Xiao, F., Sun, X., & Huang, Q. (2020). A blockchain-based scheme for privacy-preserving and secure sharing of medical data. Computers & Security, 99, 102010. https://doi.org/10.1016/j.cose.2020.102010

Ismail, L., & Materwala, H. (2020). Paradigma Blockchain para saúde: avaliação de desempenho. Symmetry, 12(8), 1200. https://doi.org/10.3390/sym12081200

Junqueira, N. R. (2020). Concessão de Permissão a Dados de Saúde Baseada em Contratos Inteligentes em Plataforma de Blockchain. Recuperado de http://repositorio.bc.ufg.br/tede/handle/tede/10400

Kara-Junior, N. (2019). Ophthalmology 4.0. Revista Brasileira de Oftalmologia, 78(3), 157-158. https://doi.org/10.5935/0034-7280.20190118

Kurose, J. F. & Ross, K. W. (2006). Computer Networks and the Internet. São Paulo: Person, 28.

Kraus, S., Schiavone, F., Pluzhnikova, A., & Invernizzi, A. C. (2021). Digital transformation in healthcare: Analyzing the current state-of-research. Journal of Business Research, 123, 557-567. https://doi.org/10.1016/j.jbusres.2020.10.030

Liang, X., Shetty, S., Tosh, D., Bowden, D., Njilla, L., & Kamhoua, C., 2018. Blockchain has enabled the sharing and collaboration of trusted and responsible data in mobile healthcare applications. EAI-endorsed transactions in comprehensive health and technology 4. http://dx.doi.org/10.4108/eai.24-7-2018.159338

Lobo, M. S. (2021). Proposta de programa de formação complementar em saúde 4.0. Recuperado de https://repositorio.unifesp.br/handle/11600/61920

Makin, S. (2021). A lacuna da prática de pesquisa como uma fronteira pragmática do conhecimento Informação e Organização. https://doi.org/10.5585/gep.v12i3.17227

Massaro, M. (2021). Transformação digital no setor de saúde por meio da tecnologia blockchain. Insights de pesquisas acadêmicas e desenvolvimentos de negócios. Technovation. Recuperado de https://ubibliorum.ubi.pt/handle/10400.6/14152

Massaro, M., Dal Mas, F., Chiappetta, J. C. J., & Bagnoli, C. (2020). Criptoeconomia e novos modelos de negócios sustentáveis: Reflexões e projeções usando uma análise de estudo de caso. Responsabilidade Social Corporativa e Gestão Ambiental, 27 (5), 2150-2160. https://doi.org/10.1002/csr.1954

Mayer, A. H., Da Costa, C.A., & Righi, R. D. R. (2020). Registros eletrônicos de saúde em um Blockchain: uma revisão sistemática. Saúde Inf. J. 26, 1273-1288. https://doi.org/10.1177/1460458219866350

Mendonça, R. D., Gomes, O. S., Vieira, A. B., & Nacif, J. A. (2021). Tratamento de Concessão e Revogação de Acesso a Registros Eletrônicos de Saúde em Blockchain. In: Anais do IV Workshop em Blockchain: Teoria, Tecnologias e Aplicações. (pp. 100-113). SBC. https://doi.org/10.5753/wblockchain.2021.17133

Nakamoto, S. (2008). Bitcoin: A peer-to-peer electronic cash system. Decentralized Business Review, 21260. Recuperado de https://www.ussc.gov/sites/default/files/pdf/training/annual-national-training-seminar/2018/Emerging_Tech_Bitcoin_Crypto.pdf

Nascimento, F. R. A. (2018). Transparência nas filas de cirurgias eletivas realizadas com recursos do SUS através da tecnologia Blockchain. Relatórios Técnicos do Departamento de Informática Aplicada da Universidade Federal do Estado do Rio de Janeiro (UNIRIO). https://doi.org/10.13140/RG.2.2.27815.19364

Nayak, B., & Bhattacharyya, S. S. (2020). A narrativa em mudança no setor de seguros de saúde: tecnologia vestível em produtos e serviços de seguros de saúde para o mundo COVID-19. Journal of Health Management, 22(4), 550-558. https://doi.org/10.1177/0972063420983

Preneel, B. (1994). Cryptographic hash functions. European Transactions on Telecommunications, 5(4), 431-448. https://doi.org/10.1002/ett.4460050406

Santos, A. C., Firmino, R. M., Soto, J. C., Medeiros, D. S., Mattos, D. M., Albuquerque, C. V., ... & Fernandes, N. C. (2020). Aplicações em redes de sensores na área da saúde e gerenciamento de dados médicos: tecnologias em ascensão. Sociedade Brasileira de Computação. https://doi.org/10.5753/sbc.4710.8.4

Schmitz, C. A. A., Gonçalves, M. R., Umpierre, R. N., Da Silva Siqueira, A. C., D'ávila, O. P., Bastos, C. G. M., ... & Harzheim, E. (2017). Teleconsulta: nova fronteira da interação entre médicos e pacientes. Revista Brasileira de Medicina de Família e Comunidade, 12(39), 1-7. Recuperado de https://lume.ufrgs.br/handle/10183/187809

Shahnaz, A., Qamar, U., & Khalid, A. (2019). Using Blockchain for Electronic Health Records. IEEE Access 7: 147782–147795. https://doi.org/10.1109/ACCESS.2019.2946373

Silva, V. F. D. (2019). Registros eletrônicos de saúde e pesquisa clínica: ferramentas para permitir um uso adequado e descentralizado de informações. Recuperado de https://periodicos.ufba.br/index.php/RFD/article/view/59912

Silva, L. V. G. D. (2020). Saúde Digital: a Interoperabilidade e a Tecnologia Blockchain (Doctoral dissertation). Recuperado de http://hdl.handle.net/10400.6/10600

Simões, S. M., Oliveira, A., & Dos Santos, M. A. (2020). Telemedicina na pandemia COVID-19. Revista Interdisciplinar de Pesquisa e Inovação, 7(2), 104-109. Recuperado de https://periodicos.ufs.br/revipi/article/view/14220

Swan, M. (2015). Blockchain: Blueprint for a new economy. " O'Reilly Media, Inc”.

Tandon, A., Dhir, A., Islam, AN & Mäntymäki, M. (2020). Blockchain na área de saúde: uma revisão sistemática da literatura, que sintetiza a estrutura e a agenda de pesquisas futuras. Computadores na Indústria, 122, https://doi.org/10.1016/j.compind.2020.103290

Taghizadegan, S. (2010). Essentials of lean six sigma. Elsevier.

Toufaily, E., Zalan, T., & Dhaou, S. (2021). Uma estrutura de tecnologia blockchain adoção: uma investigação de desafios e valor esperado. Inf. Gerenciar 58. https://doi.org/10.1016/j.im.2021.103444

Ulrich, F. (2014). Bitcoin: a moeda na era digital. ed. São Paulo: LVM Editora, São Paulo.

Vanti, N. A. P. (2002). Da bibliometria à webometria: uma exploração conceitual dos mecanismos utilizados para medir o registro da informação e a difusão do conhecimento. Ciência da informação, 31, 369-379. https://doi.org/10.1590/S0100-19652002000200016

Viana, C., Brandao, A., Dias, D., Castellano, G., & DE Paiva Guimaraes, M. (2020). Blockchain para gerenciamento de prontuários eletrônicos. Revista ibérica de sistemas e tecnologias de informação, (E28), 177-187. Recuperado de https://www.risti.xyz/issues/ristie28.pdf

Yadav, P. (2015). Cadeias de fornecimento de produtos de saúde em países em desenvolvimento: diagnóstico das causas do mau desempenho e uma agenda de reforma. Health Systems and Reform, 1, 142–154. https://doi.org/10.4161/23288604.2014.968005

Xavier, A. C. C., & Duque, C. G. (2021). Prontuário eletrônico do paciente: qual a contribuição da arquivística e do Smart Contracts para a sua gestão na Era da Saúde 4.0? AtoZ: novas práticas em informação e conhecimento, 10(3), 1-10. Recuperado de https://revistas.ufpr.br/atoz/article/view/81267

Weiss, M. C. (2019). Sociedade sensoriada: a sociedade da transformação digital. Estudos avançados, 33, 203-214. Recuperado de https://www.revistas.usp.br/eav/article/view/159485

Published

2024-08-24

How to Cite

Santos, B. E. C. dos, Silva, F. A. da, Araújo, A. C. B. de, & Pimentel, C. A. (2024). Blockchain applied in healthcare: a bibliometric review . Brazilian Journal of Production Engineering, 10(3), 355–371. https://doi.org/10.47456/bjpe.v10i3.45125

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