Evaluation of flow, pH and buffer capacity of saliva in the gestational and post-breastfeeding period: a prospective case-control study

Authors

  • Carolini Contreiro Azevedo
  • Manoelito Ferreira Silva Júnior Professor Colaborador do Departamento de Odontologia da Universidade Estadual de Ponta Grossa. http://orcid.org/0000-0001-8837-5912
  • Antônio Augusto Gomes
  • Ana Paula Martins Gomes
  • Ana Maria Martins Gomes

DOI:

https://doi.org/10.47456/rbps.v24i1.23034

Keywords:

Pregnant women, Postpartum period, Saliva, Secretory rate, Acidity

Abstract

Introduction: There is still divergence in the literature about salivary changes during the gestational period. Objectives: To evaluate the flow, pH and buffer capacity of the saliva of women in the gestational and postpartum period and compare it with non-pregnant women. Methods: The prospective case-control study with convenience sample between pregnant (P) and non-pregnant women (NP). The stimulated collection was performed in the morning during gestation and powder-delivery. Data were analyzed by the Shapiro-Wilk, t-Student, Mann-Whitney and Friedman tests (p <0.05). Results: There were 17 pregnant, with a mean age of 26.1 ± 4.4 years old; and 28 non-pregnant women, with an average of 24.4 ± 4.4 years old. There was a difference in salivary flow (p=0.023) and in the buffer capacity (p=0.033) between P and NP in the postpartum period, as well as in saliva pH at 20th (p=0.007) and 30th weeks (p=0.010) of gestation. In the group of pregnant women, saliva flow and pH did not change during gestation and postpartum (p> 0.05). However, the saliva buffer capacity increased postpartum (p <0.001). Conclusion: The salivary flow and buffer capacity of the pregnant women were lower in the postpartum period, and the saliva pH was lower in the gestational period (20th and 30th weeks) when compared to the group of non-pregnant women. Among the pregnant women, there was no change in the salivary flow and pH of the saliva, but there was an increase in the buffer capacity of the saliva at follow-up time.

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Author Biography

Manoelito Ferreira Silva Júnior, Professor Colaborador do Departamento de Odontologia da Universidade Estadual de Ponta Grossa.

Suas linhas de pesquisas abordam os temas: Educação e Saúde, Integração Ensino-Serviço, Saúde Coletiva, Epidemiologia, Odontopediatria, Clareamento Dental e Dentifrícios. Esteve ligado ao Programa Institucional Voluntário de Iniciação Científica da Universidade Federal do Espírito Santo (UFES) (2010-2011) e do Programa Institucional de Bolsa de Iniciação Científica da UFES  com financiamento da própria instituição (2012-2013) e da Fundação de Amparo a Pesquisa do Espírito Santo (FAPES) (2013-2014). Tem experiência em pesquisa multicêntrica com a Universidade Federal do Rio Grande do Norte. Foi Vice-Presidente do Centro Acadêmico de Odontologia da UFES (2013-2014) e Presidente da XXXVII Jornada Universitária Capixaba de Odontologia (JUNCO) realizada em Vitória-ES (2013). Teve a experiência de ser relator no XXX Congresso Nacional da Comissão Nacional dos Secretários Municipais de Saúde (CONASEMS) realizado na Serra-ES em 2014. Foi Coordenador das Comunicação Orais Cuidado em Saúde do 11º Congresso Brasileiro de Saúde Coletiva. Recebeu 10 prêmios/menções honrosas em eventos científicos com pesquisas realizadas. Apresenta 14 artigos publicados em revistas científicas nacionais e internacionais e 2 artigos aceitos para publicação. Aprovado em 1º Lugar no nível mestrado (2013) e doutorado (2015) no Programa de Pós-Graduação de Odontologia (Saúde Coletiva) da Faculdade de Odontologia de Piracicaba - Universidade Estadual de Campinas (FOP-UNICAMP). Recebeu bolsa de mestrado pela Fapesp (2014/15184-2) e de doutorado pela CAPES.

References

Pedersen AM, Bardow A, Jensen SB, Nauntofte B. Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Diseases. 2002;8(3):117-29.

Edgar WM. Saliva: its secretion, composition and functions. British Dental Journal, 1992;172(9):305-12.

Dawes C. Physiological factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry moth in man. JDR. 1987;66:648-53.

Tenovuo J. Funções protetoras da saliva. In: Edgar M, Dawes C, O´Mullane D. Saliva e saúde bucal: composição, funções e efeitos protetores. 3ª ed. São Paulo: Santos, 2010;103-19.

Dawes C. Fatores que influenciam na velocidade do fluxo e composição da saliva. In: Edgar M, Dawes C, O´Mullane D. Saliva e saúde bucal: composição, funções e efeitos protetores. 3ª ed. São Paulo: Santos, 2010;32-49.

Nauntofte B, Tenovuo JO, Lagerlöf F. Secreção e composição da saliva. In: Fejerskov O, Kidd, E. Cárie Dentária: a doença e seu tratamento clínico. São Paulo: Editora Santos, 2005;7-27.

Heintze UFL, Birkhed D, Björn H. Secretion rate and buffer effect of resting and stimulated whole saliva as a function of age and sex. Swed Dent J. 1983;7(6):227-38.

Laine MA. Effect of pregnancy on periodontal and dental health. Acta Odontol Scand. 2002;60(5):257-64.

Cunningham FG, Leveno KJ, Bloom SL, Spong CY, Dashe JS, Hoffman BL, Casey BM, Sheffield JS. Obstetrícia de Willian. 24 ed. Porto Alegre: AMGH Editora Ltda, 2016;107.

Laine M, Tenovuo J, Lehtonen OP, Ojanotko-Harri A, Vilja P, Tuohimaa P. Pregnancy-related changes in human whole saliva. Arch Oral Biol. 1988;33(12):913-7.

Martinez-Pabon MC, Martínez DCM, López-Palacio AM, Patiño-Gómez LM, Arango-Pérez EA. The physicochemical and microbiological characteristics of saliva during and after pregnancy. Rev Salud Pública. 2014;16(1):128-38.

Schipper RG, Silletti E, Vingerhoeds MH. Saliva as research material: Biochemical, physicochemical and practical aspects. Arch Oral Biol., 2007; 52(12):1114-35.

Laine M, Pienihäkkinen K, Ojanotko-Harri A, Tenovuo J. Effects of low-dose oral contraceptives on female whole saliva. Arch Oral Biol. 1991;36(7):549-52.

Öztürk LK, Akyüz S, Garan A, Yarat A. Salivary and dental - oral hygiene parameters in 3rd trimester of pregnancy and early lactation: the effect of education. Marmara Dent J. 2013;1:1-8.

Rio R, Azevedo A, Simões-Silva L, Marinho J, Silva MJ, Sampaio-Maia B. The biochemistry of saliva throughout pregnancy. Medical Express. 2015,2(5):1-6.

Leal AO, Rolim JIA, Muniz IAF, Muniz IAF, Farias IAP. Estudo dos parâmetros salivares de gestantes. Odontol Clín-Cient. 2013;12(1):29-42.

D’Alessandro S, Curbelo HM, Tumilasci OR, Tessler JA, Houssay AB. Changes in human parotid salivary protein and acid levels during pregnancy. Arch Oral Biol. 1989;34(10):829-31.

Kivela J, Laine M, Parkkila S, Rajaniemi H. Salivary carbonic anhydrase VI and its relation to salivary flow rate and buffer capacity in pregnant and non-pregnant women. Arch Oral Biol. 2003;48(8):547-51.

Hugoson A. Salivary secretion in pregnancy a longitudinal study of flow rate, total protein, sodium, potassium and calcium concentration in parotid saliva from pregnant women. Acta Odontol Scand. 1972;30(1):49-66.

Rockenbach MI, Marinho SA, Veeck EB, Lindemann L, Shinkai RS. Salivary flow rate, pH, and concentrations of calcium, phosphate, and sIgA in Brazilian pregnant and non-pregnant women. Head Face Med. 2006;2(44):1-5.

González M, Oca LM, Jiménez. Cambios em la composición de la saliva de pacientes gestantes y no gestantes. Perinatol Reprod Hum. 2001; 15(3): 195-201.

Rosenthal SL, Rowen B, Vazakas AJ. Comparative analysis of saliva in pregnant and non-pregnant women. I. Calcium and pH J Dent Res. 1959;38(5):883-87.

World Health Organization. Oral heath surveys: basic methods. 4th ed. Geneva: World Heath Organization; 1997.

Greene JC, Vermillion JR. The simplified oral hygiene index. J Am Dent Assoc. 1964;68:7-13.

Schipper RG, Silletti E, Vingerhoeds MH. Saliva as research material: Biochemical, physicochemical and practical aspects. Arch Oral Biol., 2007;52(12):1114-35.

Ericsson Y. Clinical investigation of the salivary buffering action. Acta Odontol Scand. 1959;97:131-65.

Bernstine RLM, Friedman MHF. Salivation in pregnant and nonpregnant woman. Obstetric Gynecology. 1957;10(2):184-89.

Laine M, Pienihäkkinen K. Salivary buffer effect in relation to late pregnancy and postpartum. Acta Odontol Scand. 2000;58(1):8-10.

Naveen S, Asha M, Shubha Ml, Bajoria AA, Jose AA. Salivary flow rate, pH and buffering capacity in pregnant and non-pregnant women: a comparative study. JMED Res, 2014.

Salvolini E, Di Giorgio R, Curatola A, Mazzanti L, Fratto G. Biochemical modifications of human whole saliva induced by pregnancy. Br J Obstet Gynaecol. 1998;105(6):656-60.

Rocha FRCR, Bunduki CV. Repercussões da gravidez no organismo materno. In: Zugaibe M, Francisco RPV. Obstetrícia. 3ª ed. Barueri: Manole, p.154-85.

Baptista DLRFS, Henrique MLBM, Carvalho B, Francisco RPV. Pré-natal. In: Zugaibe M, Francisco RPV. Obstetrícia. 3ª ed. Barueri: Manole, p. 197-217.

Sonbul H, Ashi H, Aljahdali E. Campus G, Lingström P. The influence of pregnancy on sweet taste perception and plaque acidogenicity. Matern Child Health J. 2017;21(5):1037-46.

Fonseca JGM, Parizzi MR. Nutrição na gestante e na nutriz. In: Alves Filho N, Corrêa MD, Alves Jr. JMS, Corrêa Jr. Perinatologia Básica. 3ª ed. Rio de Janeiro: Guanabara, 2006; p. 77.

Published

2022-12-07

How to Cite

1.
Azevedo CC, Silva Júnior MF, Gomes AA, Gomes APM, Gomes AMM. Evaluation of flow, pH and buffer capacity of saliva in the gestational and post-breastfeeding period: a prospective case-control study. RBPS [Internet]. 2022 Dec. 7 [cited 2024 Nov. 22];24(1):103-1. Available from: https://periodicos.ufes.br/rbps/article/view/23034

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